Carolinas Coastal Health - Thyroid Antibodies - Carolinas Coastal Health

Thyroid Antibodies

Antimicrosomal Antibody is also known as Anti-Tissue Peroxidase (or Anti-TPO). It becomes elevated in autoimmune thyroid disease such as Hashimoto's Thyroiditis, or Graves' Disease.

Anti-Thyroglobulin Antibody also becomes elevated in some cases of autoimmune thyroiditis. It tends to be positive more frequently in Graves' Disease than Hashimotos. This test is also commonly used when following patients with thyroid cancer. In thyroid cancer patients, the Thyroglobulin test is used a marker for residual thyroid tissue. However if antibodies such as Antithyroglobulin Antibody are present, this makes the Thyroglobulin test uninterpretable.